Facilitating pyramid to horizontal oriens-alveus interneurone inputs: dual intracellular recordings in slices of rat hippocampus
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چکیده
منابع مشابه
Membrane potential and intracellular Ca2+ oscillations activated by mGluRs in hippocampal stratum oriens/alveus interneurons.
Metabotropic glutamate receptors (mGluRs) are expressed heterogeneously in hippocampal interneurons, and their signal transduction cascades remain largely unclear. We characterized an oscillatory response activated by the mGluR agonist 1S,3R-1-aminocyclopentane-1,3-dicarboxylic acid (1S,3R-ACPD) in hippocampal interneurons of stratum oriens-alveus (OA) with simultaneous whole cell current-clamp...
متن کاملMembrane Potential and Intracellular Ca Oscillations Activated by mGluRs in Hippocampal Stratum Oriens/Alveus Interneurons
Woodhall, Gavin, Christine E. Gee, Richard Robitaille, and (McBain and Dingledine 1993; Morin et al. 1996; Sah et al. Jean-Claude Lacaille. Membrane potential and intracellular Ca 1990). Interneurons of the hippocampal CA1 region receive oscillations activated by mGluRs in hippocampal stratum oriens/ major excitatory inputs from CA3 and/or CA1 pyramidal alveus interneurons. J. Neurophysiol. 81:...
متن کاملGroup I metabotropic glutamate receptor actions in oriens/alveus interneurons of rat hippocampal CA1 region.
Group I metabotropic glutamate receptors (mGluRs) are important for hippocampal interneuron function. We used whole-cell recording and confocal imaging to characterize group I mGluR actions in CA1 oriens/alveus interneurons in slices. In tetrodotoxin and ionotropic glutamate receptor antagonists, the group I mGluR specific agonist DHPG increased intradendritic Ca(2+) levels and depolarized inte...
متن کاملLocal circuit interactions between oriens/alveus interneurons and CA1 pyramidal cells in hippocampal slices: electrophysiology and morphology.
Electrophysiological and anatomical techniques were used to determine the role, in the hippocampal circuitry, of local circuit neurons located at the oriens/alveus border (O/A interneurons). Intracellular recording from these cells showed that their response characteristics were clearly nonpyramidal: high input resistance, short membrane time constant, short-duration action potential, pronounce...
متن کاملSynaptically activated calcium responses in dendrites of hippocampal oriens-alveus interneurons.
Activation of metabotropic glutamate receptors (mGluRs) by agonists increases intracellular calcium levels ([Ca(2+)](i)) in interneurons of stratum oriens/alveus (OA) of the hippocampus. We examined the mechanisms that contribute to dendritic Ca(2+) increases in these interneurons during agonist activation of mGluRs and during synaptically evoked burst discharges, using simultaneous whole cell ...
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ژورنال
عنوان ژورنال: The Journal of Physiology
سال: 1998
ISSN: 0022-3751
DOI: 10.1111/j.1469-7793.1998.185bu.x